| Autor: |
Lew, A. M., Lillehoj, E. P., Cowan, E. P., Maloy, W. L., Van Schravendijk, M. R., Coligan, J. E. |
| Předmět: |
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| Zdroj: |
Immunology; Jan1986, Vol. 57 Issue 1, p3-18, 16p |
| Abstrakt: |
The article presents information on class I genes and molecules. Class I molecules of the major histocompatibility complex were the first molecules identified as targets for the rejection of tissue grafts. Since this initial observation, extensive studies have produced considerable insight into the structure and function of this highly diverse family of molecules. The remarkable hallmark of the class I family is its unparalleled degree of genetic polymorphism and diversity. The polymorphism is reflected by the fact that multiple loci encode class I molecules, and for each locus there can be upwards of 100 alleles. The purpose of this article is to assimilate the information accumulated on the class I molecules since previous reviews. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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