Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs.

Autor:	Chinami, Masanobu, Iwabuchi, Kaoru, Muto, Yoshiteru, Uchida, Yasuhiko, Arita, Ryu, Shuraim, Rana A., Adra, Chaker N.
Předmět:	CELLULAR therapy MICRORNA RECTAL cancer CANCER treatment
Zdroj:	Clinical Case Reports; Nov2019, Vol. 7 Issue 11, p2156-2164, 9p
Abstrakt:	A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient reports good quality of life. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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