Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles.

Autor: Mehra, Chahat, Gala, Ravisha, Kakatkar, Aarti, Kumar, Vivekanand, Khurana, Raman, Chatterjee, Suchandra, Kumar, N. Naveen, Barooah, Nilotpal, Bhasikuttan, Achikanath C., Mohanty, Jyotirmayee
Předmět:
Zdroj: Chemical Communications; 12/11/2019, Vol. 55 Issue 95, p14275-14278, 4p
Abstrakt: The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene functionalized silver nanoparticles. The large upward pKa shift and enhanced stability of SGR resulting from the favorable supra-nanomolecular strategy are deciphered into an improved antibacterial drug against different pathogenic micro-organisms including multi drug resistant bacteria. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index