| Autor: |
Shams, Marissa, Kobrynski, Lisa |
| Předmět: |
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| Zdroj: |
Journal of Clinical Immunology; Nov2019, Vol. 39 Issue 8, p846-848, 3p |
| Abstrakt: |
We describe the management of a patient with ADA-deficient Severe Combined Immune Deficiency maintained on PEG-ADA treatment throughout her pregnancy. ADA-deficient SCID (ADA-SCID) is rare but accounts for approximately 15% of all SCID cases. As a result of improved outcomes with definitive treatment such as hematopoietic cell transplant (HCT) and now gene therapy, few patients remain on long-term therapy with weekly PEG-ADA enzyme replacement alone. Knowledge detailing the management of ADA-SCID patients on PEG-ADA replacement during pregnancy is valuable to clinical immunologists. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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