Trisulfides over disulfides: highly selective synthetic strategies, anti-proliferative activities and sustained H2S release profiles.

Autor: Bhattacherjee, Debojit, Sufian, Abu, Mahato, Sulendar K., Begum, Samiyara, Banerjee, Kaustav, De, Sharmistha, Srivastava, Hemant Kumar, Bhabak, Krishna P.
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Zdroj: Chemical Communications; 11/21/2019, Vol. 55 Issue 90, p13534-13537, 4p
Abstrakt: Temperature- and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na2S as a sulfur-transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than disulfides in general for a sustained release of H2S and potent anti-cancer activities. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index