| Autor: |
ROTARU, LUCIANA TEODORA, VARUT, RENATA-MARIA, NICOLAESCU, OANA, ENESCU, ANCA, PUTICIU, MONICA, FLORESCU, CRISTINA, ENESCU, AURELIA |
| Předmět: |
|
| Zdroj: |
Journal of Science & Arts; Sep2019, Vol. 19 Issue 3, p709-714, 6p |
| Abstrakt: |
In attempt to avoid prosthetic problems and possible side effects that may occur in long-term bisphosphonate treatment, a solution commonly studied in recent years is local bisphosphonate release. Thus, a higher dose can be administered in the region of interest with positive effects on reduction bone loss in the periprosthetic area, but especially on osteointegration reduction time and acceleration of prosthesis component secondary fixation. On the other hand, stable fixation is also achieved in the case of osteoporotic bone. In the present paper, we have proposed to obtain implant type structures by deposition of alendronate-hydroxyapatite compositions (HA-AL) on titanium metal substrates. The deposition of the composite directly on the metallic component was accomplished by pulsed laser evaporation technique (MAPLE). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
