The use of Sodic-Salt DNA fragments in the progression of wounds healing in diabetic foot: a case control study.
| Autor: | Boschetti, G., Marin, M., Ninkovic, S., Whisstock, C., Anichini, R., Bruseghin, M., Manzi, M., Meloni, M., Volpe, A., Pinfi, M., Silvestri, D., Rocca, V. La, Macchi, B., Brocco, E. |
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| Předmět: |
ANTI-infective agents
NUCLEOTIDE metabolism ANALYSIS of variance BACTERICIDES CHI-squared test CYTOKINES DNA HOSPITAL care ISCHEMIA POSTOPERATIVE care SALT STATISTICS T-test (Statistics) TIME WOUND healing WOUND infections DIABETIC foot TREATMENT effectiveness CASE-control method SURGICAL site DATA analysis software KARNOFSKY Performance Status MANN Whitney U Test EVALUATION |
| Zdroj: | Diabetic Foot Journal; 2019, Vol. 22 Issue 4, p12-16, 5p |
| Abstrakt: | Diabetic foot syndrome is a multifactorial condition, which often requires surgical intervention to heal. Ultra distal revascularisation and minor amputations are a valid therapeutic protocol for limb salvage in forefoot lesions involving the bone. Frequently, this approach implies a residual lesion that can be healed with various devices, such as negative pressure wound therapy (NPWT), engineered tissues and dermal substitutes. Recently, a new sodic-salt DNA fragments (SSDF) preparation became available, which aims at exerting the tissues' reconstructive action through cytokines production and nucleotide synthesis. This study aims to evaluate the usefulness of SSDF in accelerating the healing rate of diabetic residual lesions in the foot. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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