| Autor: |
Babejr, Kenneth S., Gross, Alexander S., Leyva, William H., King Jr., Lloyd E. |
| Předmět: |
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| Zdroj: |
International Journal of Dermatology; Aug1992, Vol. 31 Issue 8, p588-590, 3p |
| Abstrakt: |
The article discusses the disease pyoderma gangrenosum associated with antiphospholipid antibodies. Antiphospholipid antibodies (APLA) are immunoglobulins directed against a diverse group of phospholipid antigens. Recently, the role of APLAS in the pathogenesis of skin disease has been described. Livedo reticularis and lower extremity ulcers are the two most commonly observed lesions. Pyoderma gangrenosum (PG) is a chronic, ulcerative lesion usually found on the lower extremities. The finding of antiphospholipid antibodies in a patient with pyoderma gangrenosum suggests that the role of these antibodies in "idiopathic" and auto immune disease-related PG requires further investigation. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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