| Autor: |
Dandia, Anshu, Saini, Pratibha, Bansal, Sarika, Parewa, Vijay |
| Předmět: |
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| Zdroj: |
ChemistrySelect; 9/6/2019, Vol. 4 Issue 33, p9871-9877, 7p |
| Abstrakt: |
A Cu(I)-catalyzed straightforward synthesis of quinazolin-4(3H)- ones was attained by the reaction of 2-aminobenzonitrile with benzyl bromides. The reaction proceeds via one pot Nbenzylation / CSp3- H oxidation/ CN hydrolysis/cyclization/ sequence. Numerous controlled experiments have been carried out to establish the appropriate mechanism and prerequisite of the reactions. The process was truly selective as only quinazolinones formed as desired product over dihydrogenated quinazolinones. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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