Nano composite based drug delivery system for bone regeneration.

Autor: PRASANNA, A. P. S., THAMARAISELVI, R., NAVASUJA, G., VENKATASUBBU, G. DEVANAND
Předmět:
Zdroj: Journal of Mines, Metals & Fuels; Jan2018, Vol. 66 Issue 1, p33-35, 3p
Abstrakt: Hydroxyapatite (HA) is a bioceramic, which is present in human and animal bones. It has wide range of medical application for bone infections. The usage of novel drug delivery system for antibiotics is very important for treatment and prevention of bone infection. It is because of the lack of circulation of blood in the infected tissue which makes it difficult to have sufficient supply of antibiotics to reach the adequate therapeutic level in the affected region. To enhance the treatment, we have prepared hydroxyapatite/polyvinyl alcohol/sodium alginate/amoxicillin composite, using wet chemical method. The prepared composites were analysed by various physico-chemical methods. Hydroxyapatite nanoparticles were prepared and characterized by XRD, FTIR, TEM and Raman spectroscopy. Nano composite prepared by wet chemical method and is characterised by FTIR and SEM. This work reports the synthesis of nano composite for controlled release of drugs. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index