CARCINOID HEART DISEASE AND CARDIAC METASTASIS IN NEUROENDOCRINE TUMORS: INSIGHTS FROM PATHOLOGY TO PERSONALISED DIAGNOSTIC AND THERAPEUTIC APPROACH.

Autor: Stolniceanu, Cati Raluca, Jalloul, Wael, Constantin, Volovat, Simona, Volovat, Grierosu, Irena Cristina, Gutu, Mihai, Delianu, Carmen, Nedelcu, Irina, Matovic, Milovan, Stefanescu, Cipriana
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Zdroj: Romanian Journal of Functional & Clinical, Macro & Microscopical Anatomy & of Anthropology / Revista Româna de Anatomie Functionala si Clinica, Macro si Microscopica si de Antropologie; 2019, Vol. 18 Issue 2, p105-112, 8p
Abstrakt: Carcinoid heart disease is produced by the paraneoplastic issue of the vasoactive substances excreted by the tumor, especially serotonin and represents a major cause of mortality in patients with metastatic neuroendocrine tumors. It has been observed that approximately 50% from patients with the carcinoid syndrome occurred will develop carcinoid heart disease. Carcinoid heart disease and neuroendocrine tumors cardiac metastases and are two different items, none of ethers affect the others. Ordinarily, myocardium metastases are not often seen. The prognosis of neuroendocrine tumors patients with confirmed carcinoid heart disease has improved over the past few decades, due to the upgrading in the cardiac imaging technologies, antitumor therapies, perioperative management and cardiac surgery. A multidisciplinary approach is necessary for the complex management of patients with carcinoid heart disease, both for the systemic malignant disease and the cardiac involvement. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index