RIFAMPIN IN DERMATOLOGY.

Autor: Tsankov, Nikolai K., Kamarashev, Jivko A.
Předmět:
Zdroj: International Journal of Dermatology; Jun1993, Vol. 32 Issue 6, p401-406, 6p
Abstrakt: The article focuses on the role of Rifampin in dermatology. Rifampin was first introduced in medical practice in 1966 and has since proven to be very effective against mycobacteria and gram-positive microorganisms. Rifampin, like certain cephalosporins, contains an O-acetyl group, which is hydrolyzed by an esterase. Rifarnpm given in small doses exerts a bactericidal action on mycobacteria and gram-positive organisms. Resistance to Rifampin can be intrinsic or acquired. Some mycobacteria and gram-negative organisms are intrinsically resistant.
Databáze: Complementary Index