| Autor: |
Hua Gao, Jie-Ping Mao, Dang Wang, Xin-Ling Yang |
| Předmět: |
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| Zdroj: |
Journal of Hainan Medical University; Jun2019, Vol. 25 Issue 12, p24-27, 4p |
| Abstrakt: |
Objective: To study the association of ABCB1 gene with epilepsy in the Uygur population of Xinjiang region. Methods: In this case-control study, 232 confirmed epilepsy patients from Xinjiang affiliated Medical University from January 2017 to June 2018, and 116 were recruited in the case group and 116 healthy individuals were selected as the control group. 2 mL of the blood sample was collected from each subject, from which the DNA was extracted. The polymorphism gene was determined by polymerase chain reaction followed by restriction fragment length polymorphism. Results: No significant association was observed in C3435T alleles and genotypes with epilepsy between the case and the control groups (P>0.05), G2677T/A genotypes with epilepsy was the same as GG in both of the groups. Conclusions: The polymorphisms of C3435T gene may not be associated with epilepsy in the Uygur population from the Xinjiang region. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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