| Autor: |
Yiping Bai, Zeping Xu, Chandrashekar, Meera, Jacques, Paul J. St., Yafen Liang, Yandong Jiang, Koffi Kla, Bai, Yiping, Xu, Zeping, St Jacques, Paul J, Liang, Yafen, Jiang, Yandong, Kla, Koffi |
| Předmět: |
|
| Zdroj: |
European Journal of Anaesthesiology (Cambridge University Press); Sep2019, Vol. 36 Issue 9, p633-640, 8p |
| Abstrakt: |
Background: Continuous positive airways pressure (CPAP) with a CPAP machine and mask has been shown to be more effective at minimising hypoxaemia than other devices under deep sedation. However, the efficacy of a new and simple CPAP device for spontaneously breathing obese patients during colonoscopy is unknown.Objective: We hypothesised that oxygenation and ventilation in obese patients under deep sedation during colonoscopy using CPAP via a new nasal mask (SuperNO2VA) would be better than routine care with oxygen supplementation via a nasal cannula.Design: Randomised study.Setting: Single-centre, June 2017 to October 2017.Patients: A total of 174 patients were enrolled and randomly assigned to Mask group or Control group. Thirty-eight patients were excluded and data from 136 patients underwent final analysis.Intervention: Patients in the Mask group were provided with nasal CPAP (10 cmH2O) at an oxygen flow rate of 15 l min. In the Control group, patients were given oxygen via a nasal cannula at a flow rate of 5 l min.Main Outcome Measures: The primary outcome was elapsed time from anaesthesia induction to the first airway intervention.Results: The elapsed time from anaesthesia induction to the first airway intervention was 19 ± 10 min in the Mask group (n=63) vs. 10 ± 12 min in the Control group (n=73, P < 0.001). In all, 87.5% (56/64) of patients achieved the target CPAP value. More patients in the Control group (63%) received airway intervention than in the Mask group (22%) (P < 0.001). Hypoxaemia (pulse oximeter oxygen saturation, SpO2 < 90%) occurred more frequently in the Control group (22%) than in the Mask group (5%) (P = 0.004). Minute ventilationPostinduction/minute ventilationBaseline and minute ventilationProcedure-end/minute ventilationBaseline was lower in the Control group than in the Mask group (P = 0.007 and 0.001, respectively).Conclusion: Application of a nasal mask at a target CPAP of 10 cmH2O improves ventilation and decreases the frequency and severity of hypoxaemia.Trial Registration: NCT03139448, registered at ClinicalTrials.gov. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
