Modular Manufacturing Platform for Continuous Synthesis and Analysis of Versatile Nanomaterials.

Autor: Bomhard, Sibylle, Schramm, Jonas, Bleul, Regina, Thiermann, Raphael, Höbel, Peter, Krtschil, Ulrich, Löb, Patrick, Maskos, Michael
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Zdroj: Chemical Engineering & Technology; Oct2019, Vol. 42 Issue 10, p2085-2094, 10p
Abstrakt: Nanoparticular materials have a great potential in various fields including technical and biomedical applications; to meet the specific requirements, a good control over the particle characteristics is mandatory. Addressing this, a modular system for the automated and continuous synthesis, workup, and analysis of a broad range of nanoparticles was developed. Application examples of inorganic (silica) and organic (polymersomes, niosomes) nanoparticles demonstrate the versatility of the production platform. Modules for downstream processing via a falling‐film microreactor or tangential flow filtration are presented. The hydrodynamic size as a key parameter is acquired in real time, with an inline dynamic light scattering device. All modules are controlled and operated by a process control system. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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