| Autor: |
Siems, Werner, Dubiel, Wolfgang, Dumdey, Renate, Müller, Marianne, Rapoport, Samuel Mitjia |
| Předmět: |
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| Zdroj: |
European Journal of Biochemistry; 2/15/84, Vol. 139 Issue 1, p101-107, 7p |
| Abstrakt: |
The report deals with a detailed balance of ATP production and consumption of the rabbit reticulocyte. 1. The sum-total of ATP produced amounts to 135 mmol · 1-1 · h-1. 2. About 70% of the ATP consumption has been accounted for by specific processes. The main contributing processes are the globin synthesis with about 28%, the Na+, K+-ATPase wtth 23% and the proteolysis with more than 15%. 30% of ATP consumption has not been accounted for. 3. Cycloheximide (20 μM) leads to a dissociation between synthesis and degradation of proteins, which argues against any obligatory connection between these processes. 4. More than 90% of the lysine liberated from mitochondria by proteolysis were reutilized for the globin synthesis demonstrating the high nitrogen economy of reticulocytes. 5. Each of the ATP-consuming processes studied appears to control ATP production in an independent manner without competition with each other. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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