Abstrakt: |
Central pons lesions were increased slightly in 8.3% (9 out of 93) MS with VRF cases (mostly smokers) and specificity was reduced to 90.32 % 95%CI 82.4, 94.5, when MS with VRF was compared with non-MS with VRF. B Conclusions: b Although pons lesions are seen in a minority of patients, the presence of peripheral pons lesions is a useful discriminator for MS from vascular associated lesions and specificity does not seem to be influence by the presence of VRF in MS. The MS-severity-score, 5.15 vs. 0.88 (p=0.019), the T2 brainstem-, 1 vs. 0 (p=0.041), and the total intracranial contrast-enhancing lesion counts, 2 vs. 0 (p=0.000), were higher in patients with cranial nerve enhancement, compared to age-, disease duration-, and gender- matched MS patients. The analysis included patients with non-inflammatory neurological diseases (non-MS, n=29) and new onset multiple sclerosis (MS, n=42). [Extracted from the article] |