| Autor: |
Galanos, Chris, Lüderitz, Otto, Rietschel, Ernst Th., Westphal, Otto, Brade, Helmut, Brade, Lore, Freudenberg, Marina, Schade, U., Imoto, Masahiro, Yoshimura, Hiroyuki, Kusumoto, Shoichi, Shiba, Tetsuo |
| Předmět: |
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| Zdroj: |
European Journal of Biochemistry; 4/1/85, Vol. 148 Issue 1, p1-5, 5p |
| Abstrakt: |
The recently chemically synthesized Escherichia coli lipid A and the natural free lipid A of E. coli were compared with respect to their endotoxic activities in the following test systems: lethal toxicity, pyrogenicity, local Shwartzman reactivity, Limulus amoebocyte lysate gelation capacity, tumour necrotizing activity, B cell mitogenicity, induction of prostaglandin synthesis in macrophages, and antigenic specificity. It was found that synthetic and natural free lipid A exhibit identical activities and are indistinguishable in all tests. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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