Sequence Analyses of Cyanobacterial Bicarbonate Transporters and Their Homologues.

Autor: Von Rozycki, Torsten, Schultzel, Mark A., Saier Jr., Milton H.
Předmět:
Zdroj: Journal of Molecular Microbiology & Biotechnology; 2004, Vol. 7 Issue 3, p102-108, 7p
Abstrakt: The primary HCO3 uptake system in the cyanobacterium Synecocystis is the Na+-dependent transporter SbtA. SbtA and its homologues were identified and shown to display a common topology of ten transmembrane segments (TMSs). These proved to have arisen by an intragenic duplication event from an ancestral gene encoding a five TMS protein product. A region of SbtA shows sufficient similarity to 10 TMS ABC-type integral membrane transport proteins to suggest a common origin. Phylogenetic analyses of the SbtA family revealed two clusters of cyanobacterial homologues with all non-cyanobacterial family members outside of these two clusters. The tree topology suggests that SbtA family members display multiple transport functions. Copyright © 2004 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index