| Autor: |
Ablahad, Aween Auda, Khaleel, Ameera Kamal, Almahana, Jasim |
| Předmět: |
|
| Zdroj: |
Journal of Contemporary Medical Sciences; May/Jun2019, Vol. 5 Issue 3, p160-164, 5p |
| Abstrakt: |
Objectives The aim of this research was to study the clinical and the immunohistochemical expressions of CD34 and alpha smooth muscle actin (α-SMA) for gingival pyogenic granuloma in comparison with peripheral giant cell granuloma. Methods: Formalin fixed, paraffin-embedded biopsy specimens of 48 gingival pyogenic granuloma and 39 peripheral giant cell granuloma were used in the study. Immunohistochemical analysis for CD34 and α-SMA were studied in pyogenic granuloma (PG), peripheral giant cell granuloma (PGCG). Results: The mean numbers of the CD34 positive microvessels in PGs and PGCGs were 32.58 ± 17.778 and 22.4 ± 11.208, respectively. Statistical analysis showed a highly significant difference present between them (P < 0.01). The mean numbers of blood vessels with vascular surrounding cells non-reactive to α-SMA in PGs and PGCGs were 3.81 ± 2.228 and 10.53 ± 3.432, respectively. Statistical analysis showed a highly significant differences present between them (P < 0.01). Conclusion: The mean number of CD34 positive microvessels in PGs was significantly more than that of PGCG, but the mean number of vascular surrounding cells non-reactive to α-SMA was significantly less. This can add insight to the clinical behavior and might reflect the differences in pathogenesis of these lesions. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
