| Autor: |
Bains, Lovenish, Lal, Pawan, Chand, Tirlok, Gautam, Kamal Kishore, Beg, Mohd Yasir, Kumar, Pritesh |
| Předmět: |
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| Zdroj: |
Journal of Medical Case Reports; 8/25/2019, Vol. 13 Issue 1, pN.PAG-N.PAG, 1p |
| Abstrakt: |
Background: Musculoskeletal tuberculosis forms 10-25% of extrapulmonary tuberculosis which mainly involves the spine or weight-bearing joints. Tuberculous involvement of the sternum is a rare clinical entity even in countries where tuberculosis has high prevalence. Primary tuberculous sternal osteomyelitis accounts for approximately 0.3% of all types of tubercular osteomyelitis and the probable source appears to be extension from paratracheal or hilar lymph nodes. Despite tuberculosis being a common disease in endemic countries and worldwide, a thorough literature search of the PubMed database for keywords "primary tuberculosis of sternum" and "primary tuberculous osteomyelitis of sternum" yielded 30 and 22 articles, respectively.Case Presentation: We present an unusual case of a large dumb-bell-shaped cold abscess arising due to infection of the sternum. A 23-year-old immunocompetent Asian woman presented with a gradually progressing painless swelling on anterior chest wall for the last 5 months. She had a large visible swelling on anterior chest wall which was 12.5 cm in diameter, soft, non-tender, temperature was not raised, and fluctuant. Magnetic resonance imaging showed a large dumb-bell-shaped hyperintense collection in upper anterior chest wall with marrow edema and cortical irregularity in left side of manubrium. Pus was positive for nucleic acid testing (cartridge-based nucleic acid amplification test) for Mycobacterium tuberculosis and later culture was also positive. She was started on anti-tubercular therapy and aspirated twice. Currently, she has completed 6 months of therapy and the swelling has now disappeared.Discussion: Swelling, pain localized to sternum, or ulceration of the skin with discharging sinus along with or without constitutional symptoms are the usual presentation. A high element of suspicion is needed for early diagnosis and treatment to prevent its complications. Sternal mycobacterial infections are categorized as primary, secondary, and/or acquired postoperatively. Although radiological investigations aid in diagnosis, the diagnosis is established by positive culture or histopathological examination. Anti-tubercular therapy is the mainstay of treatment with standard four-drug regimen for 6-9 months. Surgical drainage of the abscess should be considered only if it does not resolve by aspiration and anti-tubercular therapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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