| Autor: |
Pozhar, K. V., Litinskaia, E. L., Rudenko, P. A., Bazaev, N. A. |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2019, Vol. 2140 Issue 1, p020050-1-020050-3, 3p |
| Abstrakt: |
The work is dedicated to animal trials of closed-loop insulin delivery system with non-invasive NIR-spectroscopic glucose monitor and model predictive control based on empirical sigma-model of BG dynamics. The trials were aimed on verification of safety and efficiency of the smartphone controlled closed-loop operation in interaction with living organism. As a subject of trials 1 female outbred dog with steroid diabetes were used. During 24 hours closed-loop worked in automatic insulin therapy mode with defined BG maintaining ranges 75–150 and 75–250 mg/dl (each for 12 hours). The tests showed that mean absolute percentage error was less than 23 % in BG range 50–100 mg/dl and less than 20 % in BG range of 100–250 mg/dl. 95.8 % of measurements fall in zones A and B (Clarke error grid). The closed loop enables to maintain animal BG in defined ranges with maximum deviation of 22.1 %. Since during the experiment no battery-low messages were displayed, continuous operation time was more than 24 hours. The animal trials results fir with investigation tests. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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