3‐(α‐Chlorobenzyl)quinoxalin‐2(1H)‐ones as Versatile Reagents for the Synthesis of 3‐Benzylquinoxalin‐2(1H)‐ones and Thiazolo[3,4‐a]quinoxalin‐4(5H)‐ones.

Autor: Mamedov, Vakhid A., Zhukova, Nataliya A., Syakaev, Victor V., Beschastnova, Tat'yana N., Kadyrova, Milyausha S., Isaeva, Anastasiya O., Mamedova, Sevil V., Gavrilova, Elena L., Latypov, Shamil K., Sinyashin, Oleg G.
Předmět:
Zdroj: Journal of Heterocyclic Chemistry; Aug2019, Vol. 56 Issue 8, p2221-2234, 14p
Abstrakt: Facile and efficient methods for the synthesis of 3‐benzylquinoxalin‐2(1H)‐ones and thiazolo[3,4‐a]quinoxalin‐4(5H)‐ones by the reaction of the readily available 3‐(α‐chlorobenzyl)quinoxalin‐2(1H)‐ones and thiourea have been developed, with multiple roles of the latter. Possible mechanisms are discussed. These two‐step sequences can be performed in a one‐pot manner to produce the desired products in moderate to high yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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