Abstrakt: |
Fish have been the focus of many ecotoxicological studies since they are located at the top of the aquatic food chain. In recent years, industrial development and agricultural processes have resulted in increased levels of toxic metals in the environment. Cadmium is widely used in several industries and is a well known toxic pollutant. The major uses of cadmium include electroplating, pigment production, and manufacturing of plastic stabilizers and batteries. In ecotoxicological studies, cadmium has been implicated as a cause of various deleterious effects in fish .Cadmium has been shown to cause pathological changes of varying severity in several organs, such as gill, liver and kidney. The aim of the present study was to investigate the immunological and histopathological alterations induced in head and distal part of kidney due to Cadmium Chloride exposure in Channa marulius which is an important food fish of Meerut (Uttar Pradesh) region. Kidneys from fishes exposed to sublethal concentration of cadmium for 4 days (96h) showed severe alterations in head kidney, most prominent changes were depletion of the haematopoietic precursors, melanomacrophage centres, basophils were found near blood vessels, and there were empty spaces between cells. In distal part of the kidney changes observed were swelling and hypertrophy of tubules with nuclear deterioration and pyknosis. [ABSTRACT FROM AUTHOR] |