| Abstrakt: |
Childhood acute lymphoblastic leukemia and lymphoma survivors constitute the most numerous sub-group among pediatric cancer survivors. With improvement in cure rates the clinical focus shifts towards the late effects of treatment. Second tumors, cardiovascular complications, metabolic syndrome, hormonal deficits and decreased bone mineral density usually present at an young age, have a progressive course and are potentiated by aging. Their medical impact, the high social cost of the disabilities they frequently engender, the knowledge about risk factors and the possibilities for prevention at an early stage all highlight the need for a risk-oriented and life-long health care, including specific screening, careful observation and timely intervention. The following review focuses on some of the most frequent late effects and the current recommendations concerning the childhood leukemia and lymphoma survivors’ follow-up. [ABSTRACT FROM AUTHOR] |
