Molecular Analysis of Plasmodium ovale Variants.

Autor: Win, Thin Thida, Jalloh, Amadu, Tantular, Indah Setyawati, Tsuboi, Takafumi, Ferreira, Marcelo Urbano, Kimura, Masatsugu, Kawamoto, Fumihiko
Předmět:
Zdroj: Emerging Infectious Diseases; Jul2004, Vol. 10 Issue 7, p1235-1240, 6p, 1 Black and White Photograph, 1 Diagram, 3 Charts
Abstrakt: Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1-3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1-2) in each classic-type isolate. Pov 1-3 were closer to sequences previously found in the Cameroon and MAL/MAI isolates, whereas Poc 1-2 were closer to sequences previously found in two clones of the Nigerian I/CDC strain. The 3' half of Pov 1-3 was identical to the partial sequence of the SSUrRNA gene from the London School (LS) strain. Results support grouping P. ovale into two groups, the classic type (including the Nigerian I/CDC strain) and the variant type (Cameroon, MAL/MAI, and LS isolates). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index