Effect of styrylpyrone derivative (SPD) and SPD/foscarnet combination towards virus infected cell.

Autor: Ibrahim, Nazlina, Shahar, Saleha, Abdul Wahab, Noor Zarina, Nor, Norefrina Shafinaz Md.
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Zdroj: AIP Conference Proceedings; 2019, Vol. 2111 Issue 1, p040002-1-040002-4, 4p
Abstrakt: A styrylpyrone derivative (SPD) known as goniothalamin is a compound isolated from Goniothalamus umbrosus. Herein, we showed SPD inhibition of human herpes virus type-1 (HHV-1) infection. In addition, the possible mechanism of anti-HHV-1 activity was proposed through a combination treatment between SPD and commercial anti-herpetic drug, Foscarnet (PFA). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index