Antibacterial activity of [1Fe-2S]- and [2Fe-2S]-nitrosyl complexes as nitric oxide donors.

Autor:	Mumyatova, V. A., Kozub, G. I., Kondrat'eva, T. A., Terent'ev, A. A., Sanina, N. A.
Předmět:	NITROSYL compounds NITRIC oxide MICROCOCCUS luteus GRAM-positive bacteria GRAM-negative bacteria GROUP rings
Zdroj:	Russian Chemical Bulletin; May2019, Vol. 68 Issue 5, p1025-1030, 6p
Abstrakt:	The biological activity of a series of sulfur-nitrosyl iron complexes (NICs) depends on the structure of the ligands and the position of the functional groups in the aromatic ring of the ligand. Differences in susceptibility of the gram-positive and gram-negative bacteria to the NICs was found. The series of the studied NICs suppresses the formation of biofilms of Micrococcus luteus bacteria. The obtained results demonstrate that the studied complexes can serve as the basis for the preparation of antibacterial agents. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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