| Autor: |
Stiegler, Gabriele, Stohlawetz, Petra, Brugger, Stefan, Jilma, Bernd, Vierhapper, Heinrich, Höcker, Paul, Panzer, Simon |
| Předmět: |
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| Zdroj: |
British Journal of Haematology; Jun98, Vol. 101 Issue 4, p656-658, 3p |
| Abstrakt: |
We studied thrombopoietic activity in hyperthyroidism by determination of reticulated platelet counts. At the time of hyperthyroidism 14/15 patients had higher reticulated platelets than after achievement of euthyroidism (P < 0.001). There was no difference in peripheral platelet counts and mean platelet volumes at the time of hyperthyroidism when compared to euthyroidism. Three patients had pan- and auto-reactive platelet antibodies during hyperthyroidism. These antibodies were directed against GPIIb/IIIa in two patients and against GPIb/IX in one patient. Our findings provide direct evidence that hyperthyroidism is associated with increased platelet production, as reflected by an increase in reticulated platelets. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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