The structure of the O-specific polysaccharide of Proteus penneri 52.

Autor: Sidorczyk, Zygmunt, Zych, Krystyna, Świerzko, Anna, Vinogradov, Eugeny V., Knirel, Yuriy A.
Předmět:
Zdroj: European Journal of Biochemistry; 8/15/96, Vol. 240 Issue 1, p245-251, 7p
Abstrakt: An acidic O-specific polysaccharide isolated from Proteus penneri 52 contains D-galacturonic acid, 2-acetamido-2-deoxy-D-glucose, and 2-acetamido-2-deoxy-D-galactose in the ratio 1:2:2. On the basis of sugar analysis and NMR spectroscopy, which included one-dimensional TOCSY, two-dimensional COSY, heteronuclear 13C, 1H-COSY, and rotating-frame NOE spectroscopy, the following structure of the pentasaccharide repeating unit of the O-specific polysaccharide was established: β-D-GlcpNAc 1↓3→4)-β-D-GalpA-(1→3)-β-D-GlcpNAc-(1→4)-β-D-GalpNAc-(1→3)-α-D-GalpNac-(1→ Cross-reactivity of the anti-P-penneri 52 O-serum with other strains of P. penneri isolated in Germany, Poland, USA, and Canada is discussed and a new Proteus serogroup is proposed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index