Polyclonal B-cell activating capacities of gram-positive bacteria frequently isolated from periodontally diseased sites.

Autor: Donaldson, S. L., Bick, P. H., Moore, W. E. C., Ranney, R. R., Burmeister, J. A., Tew, J. G.
Předmět:
Zdroj: Journal of Periodontal Research; 1982, Vol. 17 Issue 6, p569-575, 7p
Abstrakt: The objective of this study was to determine whether gram-positive organisms frequently isolated from the periodontium in health and disease contain polyclonal B-cell activators. Extracts from numerous bacterial strains including Actinomyces viscosus,Actinomyces israelii, Actinomyces NV, Eubacterium nodatum, Eubacterium brachy, Streptococcus sanguis, Streptococcus anginosus, and Peptostreptococcus micros were tested. All of the organisms contained activity above background, but none of the activators were more potent than pokeweed mitogen, and most were less than half as potent. The actinomyces appeared to be more active than the eubacteria, streptococci, or peptostreptococci. These PBAs could be significant virulence factors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index