Clinically Relevant Response to Cisplatin-5-Fluorouracyl in Intestinal-Type Sinonasal Adenocarcinoma with Loss of Vision: A Case Report.

Autor:	Claus, Jonas, Jorissen, Mark, Vander Poorten, Vincent, Nuyts, Sandra, Hermans, Robert, Casteels, Ingele, Clement, Paul M.J.
Předmět:	ADENOCARCINOMA VISION OPTIC nerve PALLIATIVE treatment DISEASE progression
Zdroj:	Case Reports in Oncology; 2019, Vol. 12 Issue 1, p277-281, 5p
Abstrakt:	A 68-year-old man presented with rapid progressive visual loss caused by a progressive local invasive sinonasal intestinal-type adenocarcinoma (ITAC) with intracranial invasion. The local relapse of ITAC in the ethmoid sinus was previously treated with palliative radiotherapy and carboplatin-paclitaxel, without response, hence disease progression was seen. Ophthalmological examination revealed irreversible blindness of the left eye and a dramatic progressive visual loss of the right eye. Due to important visual loss caused by optic nerve invasion, a palliative treatment with cisplatin-5-fluorouracyl was started. This therapy resulted in a good clinical response with a regression of the local mass and a partial recovery of the vision. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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