| Autor: |
Tran, Phi Hung, Le, Viet Dung, Do, Thi Ha, Nguyen, Thi Luyen, Nguyen, Phuong Thao, Nguyen, Trong Thong, Nguyen, Tien Dat |
| Zdroj: |
Natural Product Research; Mar2019, Vol. 33 Issue 5, p695-700, 6p |
| Abstrakt: |
One new and three known compounds were isolated from the ethanol extract of Psychotria prainii aerial parts. By means of spectroscopic methods, their structures were elucidated to be deacetylasperulosidic acid 6-ethyl ether (1), asperulosidic acid (2), asperuloside (3) and obtucarbamates C (4). The isolated compounds were evaluated for their inhibitory effect on NO production in LPS-stimulated RAW264.7 cells. Among them, compounds 2 and 4 exhibited strong effect with the IC50 values of 5.75 ± 0.85 and 6.92 ± 0.43 μM, respectively. This is the first report for the chemical composition and biological activity of P. prainii. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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