Short-Term Complications in Preterm Infants with Respiratory Distress Syndrome Treated with Rapid Extubation of Tracheal Tube Following Administration of Surfactant (INSURE) and Mechanical Ventilation Methods.

Autor: Kazemian, Fahimeh, Arzani, Afsaneh, Haghshenas, Mohsen, Akbarian, Zahra
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Zdroj: Pars Journal of Medical Sciences; Winter2016, Vol. 14 Issue 4, p1-7, 7p
Abstrakt: Introduction: Surfactant injection is used for treatment of respiratory distress syndrome in preterm infants through Intubation-SURfactant-Rapid Extubation and conventional mechanical ventilation. This study aimed to compare the prematurity complications in neonates treated with one of these two methods. Material and methods: This descriptive study examined records of 120 preterm neonates hospitalized in NICUs of hospitals affiliated to Babol University of Medical Sciences in 2012-2013. Eligible neonates were non-randomly assigned to conventional treatment based on the admission year (mechanical ventilation in 2012 and Intubation-SURfactant-Rapid Extubation in 2013). Required variables extracted from their records were entered into the questionnaires. Data were analyzed by SPSS version 14 and p<0.05 was considered significant. Results: The results showed that death, intraventricular hemorrhage, seminated intravascular coagulation (p=0.01), retinopathy of prematurity (p=0.03) and pneumothorax (p=0.001) were significantly less in the INSURE group than in the mechanical ventilation group. However, no significant difference was observed between the two groups regarding the pulmonary hemorrhage (p=0.4), sepsis (p=0.29) and patent ductus arteriosus (p=0.24). Conclusion: Based on the findings of this study, INSURE method is safer than mechinaical ventilation in preterm infants with respiratory distress. Therefore, further studies are suggested in order to use this method for treatment of respiratory distress syndrome in neonatal intensive care units. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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