| Autor: |
Pasmatzi, Efstathia, Monastirli, Alexandra, Badavanis, George, Papadionysiou, Christina, Tsambaos, Dionysios |
| Předmět: |
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| Zdroj: |
Hospital Chronicles; 2018, Vol. 13 Issue 1-4, p19-26, 8p |
| Abstrakt: |
Galectins constitute a family of β-galactoside-binding proteins (lectins) that are widely distributed in nature occurring in mammals, sponges, fungi, nematodes, insects and viruses. Galectins are involved in fundamental cellular processes in human skin and other tissues. They exert biological effects of considerable importance through interactions with cytoplasmic and nuclear proteins, as well as with components of cell surface and extracellular matrix. In this paper we summarize current knowledge on the expression of galectins 7 and 9 in normal and diseased human skin and present the future perspectives of the use of these galectins or their antagonists/inhibitors in the diagnosis, prognosis and treatment of cutaneous disorders. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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