Phenotypic expression of a family with multiple endocrine neoplasia type 2A due to a RET mutation at codon 618.

Autor: Lindskog, S., Nilsson, O., Jansson, S., Nilsson, B., Illerskog, A.-C., Ysander, L., Ahlman, H., Tisell, L.-E.
Předmět:
Zdroj: British Journal of Surgery; Jun2004, Vol. 91 Issue 6, p713-718, 6p, 2 Charts
Abstrakt: Reports on the phenotypic expression of a family with multiple endocrine neoplasia type 2A (MEN2A), in which serine substitutes for cysteine at codon 618 in exon 10 of the RET gene. Standard surgical treatment for medullary thyroid carcinoma; Most common of these syndromes; Factors that are important for the development and proliferation of neuroendocrine cells and the enteric nervous system.
Databáze: Complementary Index