Successful debulking of plurihormonal pituitary macroadenoma with long‐acting pasireotide and dopamine agonist combination therapy.

Autor:	Jerkins, Terri W., Jerkins, Randy K., Franklin, Robbi
Předmět:	DOPAMINE agonists SOMATOTROPIN HYPERGLYCEMIA PROLACTIN
Zdroj:	Clinical Case Reports; Mar2019, Vol. 7 Issue 3, p445-451, 7p
Abstrakt:	Key Clinical Message: Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734). Long‐acting pasireotide and bromocriptine provided biochemical control of growth hormone and prolactin in a patient with plurihormonal pituitary macroadenoma, allowing near‐complete tumor excision while restoring pituitary function and avoiding adjunctive radiotherapy. Pasireotide initiation resulted in hyperglycemia, which stabilized after a few months and resolved upon pasireotide discontinuation (ACCESS; NCT01995734). [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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