| Autor: |
Afacan-Öztürk, Hacer B., Falay, Mesude, Albayrak, Murat, Yıldız, Abdulkerim, Öztürk, Ҫiğdem Pala, Maral, Senem, Özet, Gülsüm |
| Předmět: |
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| Zdroj: |
Clinical Laboratory; 2019, Vol. 65 Issue 3, p313-314, 5p |
| Abstrakt: |
Background: Immunophenotyping has a central role in CLL. However, CLL is a very heterogenous disease, both morphologically and immunophenotypically; thus, its diagnosis may prove a challenge. We investigated CD81 expression in the differential diagnosis of CLL and MCL. Methods: We retrospectively examined CD81 expression with 8 color Multiparameter Flow cytometry devices in 101 CLL and 19 MCL cases. Results: We found negative CD81 expression in CLL cases whereas it was positive in MCL cases. Conclusions: Our results suggest that CD81 may be a valuable marker for the differential diagnosis of CLL. We are of the opinion that it should be definitely included in the diagnostic algorithm for CLL. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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