Four-component, three-step cascade reaction: an effective synthesis of indazole-fused triazolo[5,1-c]quinoxalines.

Autor: Shiva Kumar, K., Naikawadi, Praveen Kumar, Rajesham, Bandari, Rambabu, D.
Předmět:
Zdroj: New Journal of Chemistry; 3/21/2019, Vol. 43 Issue 11, p4333-4337, 5p
Abstrakt: An efficient four-component, three-step cascade reaction was developed for the synthesis of indazole-fused triazolo[5,1-c]quinoxalines from o-azido aldehyde, o-iodoaniline, phenylacetylene, and sodium azide. The methodology involves the sequential formation of 2H-indazole, then azide–alkyne cycloaddition, followed by C–N coupling, and finally intramolecular cross-dehydrogenative C–C coupling. Notable features of this protocol include simple starting materials, reduced synthetic steps, and good yields. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index