| Autor: |
Grigorian, Areg, Gambhir, Sahil, Al-Khouja, Lutfi, Gabriel, Viktor, Schubl, Sebastian D., Nastanski, Frank, Lekawa, Michael, Joe, Victor, Nahmias, Jeffry, Grigorian, Areg MD, Gambhir, Sahil MD, Al-Khouja, Lutfi MD, Gabriel, Viktor MD, Schubl, Sebastian D MD, Nastanski, Frank MD, Lekawa, Michael MD, Joe, Victor MD, Nahmias, Jeffry MD, MHPE |
| Předmět: |
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| Zdroj: |
American Journal of Drug & Alcohol Abuse; 2019, Vol. 45 Issue 1, p77-83, 7p |
| Abstrakt: |
Background: The reported incidence of venous thromboembolism (VTE) disease in trauma is 1-58% and is considered a preventable cause of mortality. Positive blood alcohol concentration (BAC) is found in 8-45% of trauma admissions; however, its association with VTE is controversial.Objectives: We hypothesized that a positive BAC on admission would be associated with a lower rate of VTE in a large national database of trauma patients.Methods: We queried the largest United States trauma registry, National Trauma Data Bank (2007-2015), for any patient with positive BAC on admission. The primary outcome was VTE and the secondary outcome was mortality. A multivariable logistic regression model was used for analysis.Results: From 2,725,032 patients (70.1% male, 29.9% female), 1,800,216 (66.1%) had a negative BAC while 924,816 (33.9%) had a positive BAC. A positive BAC was associated with lower rates of VTE (OR = 0.88, CI = 0.86-0.90, p < 0.001) and mortality (OR = 0.91, CI = 0.90-0.93, p < 0.001).Conclusion: In a large national database, trauma patients with a positive BAC were associated with a lower rate of VTE compared to those with negative BAC. Additionally, trauma patients with positive BAC had a lower association with mortality. These findings remained after adjustment of well-known risk factors for VTE and mortality, respectively. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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