| Autor: |
Alberici, I, La Manna, A, Pennesi, M, Starc, M, Scozzola, F, Nicolini, G, Toffolo, A, Marra, G, Chimenz, R, Sica, F, Maringhini, S, Monasta, L, Montini, G |
| Předmět: |
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| Zdroj: |
Acta Paediatrica; Mar2019, Vol. 108 Issue 3, p544-550, 7p |
| Abstrakt: |
Aim: In 2009, the Italian society for paediatric nephrology suggested the need for cystography, following a first febrile urinary tract infection (UTI), only in children at high risk for dilating vesicoureteral reflux or in the event of a second infection. The aim of this study was to evaluate the adequacy of the risk factors proposed by the Italian guidelines.Methods: Children aged 2-36 months, managed by 10 Italian hospitals between 2009 and 2013, with a first febrile UTI were retrospectively evaluated.Results: Four hundred and fourteen children were included: 51% female, mean age eight months. Escherichia coli was responsible of 84% UTIs. 269 children (65%) presented at least one risk factor, thus were further investigated: 44% had a reflux. The presence of a pathogen other than E. coli significantly predicted high-grade reflux, both in the univariate (Odd Ratio 2.52, 95% Confidence Interval 1.32-4.81, p < 0.005) and multivariate analysis (OR 2.74, 95% CI: 1.39-5.41, p: 0.003). 26/145 children (18%) with no risk factors experienced a second UTI, which prompted the execution of cystography, showing a dilating reflux in 11.Conclusion: Among the risk factors proposed by the Italian guidelines, only the presence of a pathogen other than E. coli significantly predicted reflux. Cystography can be postponed in children with no risk factors. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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