Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report.

Autor: Elias, N.S., Riedl, Jürgen, Stouten, Karlijn, Levin, Mark‐David, Wolfhagen, Frank, Eefting, Mathijs, Vermeer, Henricus Jan
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Zdroj: Clinical Case Reports; Jan2019, Vol. 7 Issue 1, p175-179, 5p
Abstrakt: Key Clinical Message: Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow‐up does not need any microscopic review's only flow cytometric PNH clone size. Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs‐negative hemolytic anemia combined with an increased LDH level are signs to test for PNH. Follow‐up does not need any microscopic review's only flow cytometric PNH clone size. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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