Inside Cover: A Pretreatment‐Free, Polymer‐Based Platform Prepared by Molecular Imprinting and Post‐Imprinting Modifications for Sensing Intact Exosomes (Angew. Chem. Int. Ed. 6/2019).

Autor: Mori, Kisho, Hirase, Mitsuhiro, Morishige, Takahiro, Takano, Eri, Sunayama, Hirobumi, Kitayama, Yukiya, Inubushi, Sachiko, Sasaki, Ryohei, Yashiro, Masakazu, Takeuchi, Toshifumi
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Zdroj: Angewandte Chemie International Edition; 2/4/2019, Vol. 58 Issue 6, p1522-1522, 1p
Abstrakt: A pretreatment‐free fluorescence‐based sensing platform for intact exosomes was prepared by molecular imprinting and post‐imprinting modifications. In their Communication on page 1612 ff., T. Takeuchi et al. show that by introducing antibodies and fluorescent reporter molecules only inside binding nanocavities, highly sensitive detection of exosomes without pretreatment is enabled. This exosome sensing system discriminated between normal exosomes and those originating from prostate cancer. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index