| Autor: |
Thomas, Dylan D., Anderson, Wendy A., Apovian, Caroline M., Hess, Donald T., Yu, Liqun, Velazquez, Amanda, Carmine, Brian, Istfan, Nawfal W. |
| Předmět: |
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| Zdroj: |
Obesity (19307381); Feb2019, Vol. 27 Issue 2, p217-225, 9p |
| Abstrakt: |
Objective: Weight recidivism following Roux-en-Y gastric bypass (RYGB) is common and is associated with recurrence of comorbidities. Studies with long-term follow-up of recidivism quantified by weight regain (WR) are lacking. A retrospective review of all RYGB at our center from 2004 to 2015 was performed to examine the effects of race and type 2 diabetes on WR following RYGB.Methods: Multivariable linear mixed models were used for the effects of time and race on weight, WR relative to nadir weight (WR/nadir), and WR relative to maximal weight loss, and Cox regressions were used for low, moderate, and high WR/nadir.Results: A total of 1,395 participants were identified. The sample was limited to African American (AA), Caucasian American (CA), and Hispanic American (HA) participants. The effects of time (P < 0.0001), race (P < 0.0001), and race × time interaction (P = 0.0008) on weight trajectory were significant. AA had significantly more WR than CA (P < 0.01). AA and HA had a higher hazard ratio for having low, moderate, and rapid WR/nadir.Conclusions: Racial disparities after RYGB include WR and particularly affect AA. Understanding the etiologic factors that contribute to these disparities is important to optimize the long-term clinical outcomes of bariatric surgery. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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