Viscoelastic behavior of HAp reinforced polyvinyl alcohol composite hydrogel for tissue engineered articular cartilages.

Autor: Kumar, B. Y. Santosh, Isloor, Arun M., Kumar, G. C. Mohan
Předmět:
Zdroj: AIP Conference Proceedings; 2019, Vol. 2057 Issue 1, p020062-1-020062-5, 5p
Abstrakt: Polyvinyl alcohol (PVA) hydrogels have desirable characteristics for use as a soft tissue substitute. However, their low mechanical strength and biocompatibility hinder the wide range of biomedical application. Herein, hydroxyapatite blended PVA/HAp composite hydrogel was developed by freeze-thawing and annealing method. The microstructure and rheological properties such as storage and loss modulus are investigated. Samples showed a porous structure with interconnected porosity and HAp distributed uniformly in a PVA matrix. Further, the composite hydrogel showed favorable viscoelastic properties and is suitable for artificial articular cartilage replacement. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index