Endoscopic Management of Vesicoureteral Reflux and Long-term Follow-up.

Autor: Rao, Kln, Menon, Prema, Samujh, R, Mahajan, Jk, Bawa, M, Malik, Ma, Mittal, Br
Zdroj: Indian Pediatrics; Dec2018, Vol. 55 Issue 12, p1046-1049, 4p
Abstrakt: Objectives: To report our experience with endoscopic management of vesicoureteral reflux (VUR) by injection of a tissue bulking substance-Dextranomer/ hyaluronic acid copolymer at vesicoureteric junction.Design: Retrospective analyses of case records.Setting: Pediatric Surgery department in a tertiary care government Institute.Participants: 500 children (767 renal units) consecutively referred to the out-patient department with vesicoureteral reflux noted on micturating cysto-urethrogram (MCU) over a period of 13 years (2004-2016).Intervention: Preoperative VUR grading and renal scars on radionuclide scans were documented. Dextranomer hyaluronic acid copolymer was injected through a cystoscope at the vesicoureteral junction as a day care procedure under short anesthesia. Patients were followed (average duration 27.3 mo) with clinical assessment, periodic urine cultures and renal scans.Main outcome measure: Cessation of VUR and symptomatic relief / clinical success postoperatively at 3 months.Results: Complete symptomatic relief was obtained in 482 (96.4%) patients. In 681 units where MCU was available, 614 (90%) units showed resolution of VUR.Conclusion: Endoscopic injection of tissue bulking substances at vesicoureteric junction to stop VUR seems to be an effective intervention [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index