| Autor: |
Potworowski, E. F., Lefebvre, Diane, Lussier, G., Teodorcyzk, Julita A. |
| Předmět: |
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| Zdroj: |
Immunology; Jun75, Vol. 28 Issue 6, p1115-1121, 7p |
| Abstrakt: |
An antiserum to chicken soluble thymic factor (STF) was prepared in rabbits and absorbed with chicken thymocytes until it reacted only with thymic reticuloepithelial cells. When injected into 6-day-old embryonated eggs, this antiserum caused a severe depletion of small lymphocytes in the cortical region of the thymus which was filled with large undifferentiated cells. In addition, reticuloepithelial cells displayed a marked disruption of cytoplasmic elements. The percentage of thymic lymphocytes bearing the T antigen was greatly reduced. It is believed that a factor responsible for differentiation of stem cells into T cells has been inhibited. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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