Sleep Timing, Stability, and BP in the Sueño Ancillary Study of the Hispanic Community Health Study/Study of Latinos.

Autor:	Abbott, Sabra M., Weng, Jia, Reid, Kathryn J., Daviglus, Martha L., Gallo, Linda C., Loredo, Jose S., Nyenhuis, Sharmilee M., Ramos, Alberto R., Shah, Neomi A., Sotres-Alvarez, Daniela, Patel, Sanjay R., Zee, Phyllis C.
Předmět:	HEART metabolism disorders SLEEP-wake cycle INSULIN resistance CIRCADIAN rhythms CARDIOVASCULAR disease diagnosis ACTIGRAPHY BLOOD pressure COMPARATIVE studies HISPANIC Americans INFORMATION storage & retrieval systems INSOMNIA LONGITUDINAL method RESEARCH methodology MEDICAL cooperation PUBLIC health RESEARCH SELF-evaluation SLEEP TIME EVALUATION research DISEASE incidence DISEASE prevalence CROSS-sectional method RETROSPECTIVE studies
Zdroj:	CHEST; Jan2019, Vol. 155 Issue 1, p60-68, 9p
Abstrakt:	Background: Timing and stability of the sleep-wake cycle are potential modifiable risk factors for cardiometabolic disease. The aim of this study was to evaluate the relationship between objective measures of sleep-wake timing and stability with cardiometabolic disease risk.Methods: In this multicenter, cross-sectional, population-based study, actigraphy data were obtained from the 2,156 adults, aged 18 to 64 years, recruited from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (2010-2013). These data were correlated with measures of cardiometabolic disease risk, including systolic and diastolic BPs, homeostatic assessment of insulin resistance, glycosylated hemoglobin, BMI, and hypertension and diabetes status.Results: Each 10% decrease in interdaily stability was associated with a 3.0% absolute increase in the prevalence of hypertension (95% CI, 0.6-5.3; P < .05), an increase in systolic BP by 0.78 mm Hg (95% CI, 0.12-1.45; P < .05) and an increase in diastolic BP by 0.80 mm Hg (95% CI, 0.28-1.32; P < .05). In addition, delaying the midpoint of sleep by 1 h was associated with an increase in systolic BP by 0.73 mm Hg (95% CI, 0.30-1.16; P < .01) and diastolic BP by 0.53 mm Hg (95% CI, 0.17-0.90; P < .01). These associations were not significant after adjusting for shift work status. No association was found between interdaily stability or sleep timing and diabetes, BMI, or insulin resistance.Conclusions: These results suggest that beyond sleep duration, the timing and regularity of sleep-wake schedules are related to hypertension prevalence and BP. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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