| Autor: |
He, Jianying, Zhong, Wenwen, Zhang, Ming, Zhang, Rongping, Hu, Weiyan |
| Zdroj: |
Translational Neuroscience; Jan2018, Vol. 9 Issue 1, p147-153, 7p |
| Abstrakt: |
Parkinson's disease, the second major neurodegenerative disease, has created a great impact on the elder people. Although the mechanisms underlying Parkinson's disease are not fully understood, considerable evidence suggests that neuro-inflammation, oxidative stress, mitochondrial dysfunction, cell proliferation, differentiation and apoptosis are involved in the disease. p38MAPK, an important member of the mitogen-activated protein family, controls several important functions in the cell, suggesting a potential pathogenic role in PD. This review provides a brief description of the role and mechanism of p38MAPK in Parkinson's disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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