An Efficient Two‐Step Preparation of α‐, β‐, γ‐ or δ‐Amino Acids from 2‐Pyrazinones, 2‐Hydroxypyrimidines or 2‐Pyridones Respectively.

Autor:	Zacharie, Boulos, Abbott, Shaun D., Baigent, Christopher B., Doyle, Christopher, Yalagala, Ravi Shekar
Předmět:	AMINO acid synthesis PYRAZINONES PYRIMIDINES CHEMICAL derivatives CHROMATOGRAPHIC analysis
Zdroj:	European Journal of Organic Chemistry; 12/13/2018, Vol. 2018 Issue 46, p6486-6493, 8p
Abstrakt:	A practical and efficient two‐step procedure is reported for the preparation of a variety of α‐, β‐, γ‐ and δ‐amino acids from 2‐pyridone, 2‐pyrazinone or 2‐hydroxypyrimidine and derivatives. The procedure is amenable to scale‐up and in most cases no chromatographic purification of the product is required. This approach is useful, especially in the synthesis of amino acids or deuterated amino acids that are not obtained by other methods. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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